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Berkman Klein Luncheon Series

Computer Simulations to Enhance Vaccine Trials

Digital Health @ Harvard Talk

Event will be live webcast and recorded at 12:00 pm on day of event.

Infectious disease emergencies are opportunities to test the efficacy of newly developed interventions (eg drugs, vaccines and treatment regimens), yet they raise many intertwined challenges of politics, logistics, ethics, and study design. Consistent with the efforts of CEPI, WHO, and others to encourage development and Phase I/II testing of candidate vaccines (the focus of this talk) in advance of emergencies, it is essential before the emergency strikes to advance the discussion of how such products can and should be tested. This can help to disentangle ethical from political and logistical concerns, reduce the time pressure to make a decision, and encourage rational deliberation by future stakeholders who at the time of deliberation do not know what role (which product, which field site) they may be supporting in an actual emergency.

This luncheon will describe  Professor Lipsitch’s work on computer simulation of vaccine trials during epidemics to assess options for trial design, as well as some of his recent work on the ethics of trials in emergencies, with the aim to stimulate discussion on the intersection of these two topics.

Tuesday, Nov 27, 2018
12:00 PM - 1:15 PM ET
HLS Wasserstein Hall, Milstein East C (room 2036, second floor)
1585 Massachusetts Ave
Cambridge, MA 02138 US

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