Biotechnology - Genomic and Proteomics/Data, narratives and tools produced by the BGP field

Answer the questions:

1. Define what kind of data, narratives and tools constitute the outputs of the field and its dynamics (e.g.: data in science may get better if open once it receives annotations and can be improved by other scientist).

Data

• Foundational Data
  • Big players:

• Observational Data
  • Big Players:

Narratives

• JOURNALS
  • INCUMBENTS
    • Elsevier
    • Springer
    • Wiley Blackwell
    • Thomson Reuters Science
  • CHALLENGERS
    • PubMed
    • Nature
    • BioMedCentral
      • BioMed Central is an STM (Science, Technology and Medicine) publisher which has pioneered the open access publishing model. All peer-reviewed research articles published by BioMed Central are made immediately and freely accessible online, and are licensed to allow redistribution and reuse. BioMed Central is part of Springer Science+Business Media, a leading global publisher in the STM sector.
    • Public Library of Science

• ONTOLOGIES
  • US National Center for Biomedical Ontology
  • Open Biomedical Ontologies
  • Gene Ontology

• ANNOTATIONS
  • Gene Ontology Annotation
  • Distributed Annotation System
  • Gene Wiki

Tools

Biological Materials

• Steam cells
• Plasmid
• Mice
  • Knock-out Mouse
    • Research: University of Utah
    • Funds:
    • Patent:
    • Patent Owner: University of Utah
    • Use:
    • History of patent use: "the University of Utah received a patent in 1987 but never sought to enforce the patent against follow-on researchers using the knock-out methodology. Instead, Knock-out mice were made available at (essentially) marginal cost through the Jackson Laboratory (i.e., these mice were distributed as JAX mice)." (pg 12) (Murray at all)
    • Biobank: Jax Labs
  • Onco-Mouse Mice
    • Research: Harvard
    • Funds: partially financed by DuPont and public fund of ???
    • Development: Internally by DuPOnt
    • Patent:
    • Patent Owner: DuPont
    • Use:
    • History of patent use: "As a result of their partial funding of Harvard's Oncomouse discoveries and their internal development of Cre-Lox technology, DuPont gained exclusive control over patents for these two technologies. In contrast to the University of Utah, DuPont exercised strict control over the distribution and use of mice that exploited the techniques covered by their patent portfolio. During the early 1990s, researchers (and their institutions) who wanted "freedom to operate" were obliged to obtain a license from DuPont when they sought to receive and use an Onco or Cre-Lox mouse." (pg 12) (Murray at all)
    • Biobank: Jax Labs
  • Cre-Lox Mouse
    • Research: Harvard, partially financed by DuPont
    • Funds: partially financed by DuPont and public fund of ???
    • Development: Internally by DuPOnt
    • Patent:
    • Patent Owner: DuPont
    • Use:
    • History of patent use: same as "Onco-Mouse"
    • Biobank: Jax Labs

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Bibliography for Item 3 in BGP
Biotechnology_-_Genomic_and_Proteomics